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| Healthy Homes for Kids and Pets |
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| Diabetes Mellitus |
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One of the most common metabolic diseases of dogs and cats is Diabetes Mellitus (DM). It is a complex disorder that can result from either an insulin deficiency or impaired insulin activity in the body. DM is a very serious disease and left untreated it can be life threatening. In the normal animal insulin is produced by special cells in the pancreas called "beta-islet" cells. It is released into the bloodstream and used by almost every tissue in the body to allow glucose (blood sugar) to enter individual cells and be used either as energy or storage. When there is a lack of insulin, the glucose level builds up in the bloodstream because it cannot enter cells. Once the blood sugar level reaches a certain point the kidneys can no longer reabsorb it and glucose is excreted into the urine. Elevated levels of glucose in the urine cause the body to excrete a large amount of water along with it. This is what causes diabetic animals to urinate so much. Because of this excessive loss of fluid the animal starts drinking large amounts of water to compensate. Excessive thirst and urination are typically the first signs that an owner notices once their animal develops diabetes. With the body’s normal energy pathways blocked, the body starts to burn muscle tissue and fat stores for energy. This can cause rapid weight loss in a diabetic animal, another sign that an owner may notice. Metabolism of the body fat stores for energy leads to an increased production of "fatty acids" which are eventually converted to "ketones". If the level of fatty acids and ketones rises too high, the animal may develop a serious and potentially fatal complication of DM called "ketoacidosis". DM usually strikes older animals with the average age of the pet around 8 years. A few breeds of dogs have a higher risk of developing the disease. These include Keeshonds, Miniature Pinchers, Cairn Terriers and Poodles. Female dogs seem to be more prone to the disease than males. And while there is no breed predilection for cats, male cats are more likely to develop diabetes than females. Another major risk factor for developing diabetes is obesity. Studies show that obese animals are at much greater risk of developing diabetes than a normal weight animal. Keeping your pet at its ideal weight significantly lowers its risk of developing diabetes and many other serious diseases. Diagnosis of diabetes is by accomplished by blood and urine testing. If an elevated level of glucose is present in a fasting blood sample and a urine sample the animal is most likely diabetic. A full chemistry panel should be performed to look for other diseases that may be causing the diabetes such as adrenal gland diseases, and pancreatitis. Diabetes in dogs is usually caused by destruction of the beta-islet cells in the pancreas causing a deficiency of insulin. This type of diabetes is referred to as Type 1 diabetes and must be treated with insulin injections once or twice a day. Diabetes in cats can sometimes be a mixed type where there is a decreased amount of insulin released from the pancreas and the activity of the insulin is blocked in the tissues. This is called Type 2 diabetes. Some cats can be treated with oral medications that normalize their glucose level. Others need to be given insulin injections daily. Interestingly, DM is some cats may be transient and the medications stopped after a few months. Diet therapy is an important part of managing diabetic animals. A food high in fiber such as Hills W/D helps to delay food absorption from the GI tract, thereby preventing a surge in the blood glucose level after a meal. Soft moist (pouch) foods should be avoided at all costs since they contain a lot of simple carbohydrates and cause a severe elevation in glucose levels after a meal. Hill's has developed a new diet called M/D for obese, diabetic cats. It is a low carbohydrate and many cats seem to respond quite well to it and lose weight. This diet should be tried in cats not losing weight on the traditional high fiber, low calorie foods. Although diabetes is a serious disease, many animals can live near normal lives if given the proper care. Early detection and treatment of the disease helps to prevent serious complications from developing. Owners that notice their animal having increased thirst and urination and weight loss despite a good appetite should bring their animal to their veterinarian as soon as possible for an exam. |
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